Glutamine Brain Supplement

Glutamine is an is the most abundant amino acid (building block of protein) in the bloodstream and muscle tissue: up to 60 percent of the amino acid content in skeletal muscle tissue is glutamine. It is one of the most effective brain supplements. The nutritionalist Patrick Holford calls it 'amazing brain fuel'.

Cognitive and mood effects of glutamine brain supplement

Glutamine taken as a brain supplement easily passes through the blood-brain barrier. The blood-brain barrier is the specialized membrane around blood capillaries in the brain that protects the brain from harmful substances in the blood stream (e.g. toxins, bacteria, viruses), while allowing the brain to be supplied with the required nutrients for proper function.

ENERGY. Glutamine is an important source of energy for the brain and nervous system. If the brain is not getting enough glucose, it compensates by increasing glutamine metabolism for energy. Glutamine users often report less fatigue, more energy and a more positive mood.

LEARNING & MEMORY. Inside the brain glutamine may be converted into glutamate, another amino acid that is critical to communication between neurons in the brain and synaptic plasticity. In the vertebrate nervous system, glutamate is the most abundant excitatory neuro-transmitter. Because of its role in synaptic plasticity, it is believed that glutamate is involved in cognitive functions like learning and memory in the brain. And there is evidence that glutamine supplementation aids problem solving performance.

Non-brain functions of glutamine

MUSCLES. It helps build and maintain the muscles of the body. It is manufactured in the body, but under physical stress the demand for glutamine is greater than the body's ability to make it. Because this amino acid helps to build and maintain muscle mass, supplemental glutamine may be useful for dieters or bodybuilders.

IMMUNE SYSTEM. Glutamine helps in the formation of cells such as lymphocytes and macrophages that function as part of the immune system.

Without sufficient glutamine, the immune system would cease to function. For this reason glutamine may be recommended for individuals who suffer from diseases linked to a malfunctioning immune system, such as rheumatoid arthritis or chronic fatigue.